positive

Current and former workers in workplaces with silica
exposure should be systematically screened for active TB.

People living with HIV should be systematically screened
for active TB at each visit to a health facility.

Household contacts and other close contacts should be
systematically screened for active TB.

Children living with HIV who do not have poor weight gain, fever or current cough are unlikely to
have active TB.

Providing IPT to people living with HIV does not increase the risk of developing isoniazid-resistant
TB. Therefore, concerns regarding the development of INH resistance should not be a barrier to
providing IPT.

Adults and adolescents living with HIV who have an unknown or positive TST status and who are
unlikely to have active TB should receive at least 36 months of IPT. IPT should be given to such
individuals irrespective of the degree of immunosuppression, and also those on ART, those who
have previously been treated for TB and pregnant women.

Adults and adolescents who are living with HIV, have unknown or positive tuberculin skin test
(TST) status and are unlikely to have active TB should receive at least 6 months of IPT as part of
a comprehensive package of HIV care. IPT should be given to such individuals irrespective of the
degree of immunosuppression, and also to those on ART, those who have previously been treated
for TB and pregnant women.

Adults and adolescents living with HIV should be screened with a clinical algorithm; those who
do not report any one of the symptoms of current cough, fever, weight loss or night sweats are
unlikely to have active TB and should be offered IPT.

TB patients with known positive HIV status and TB patients living in HIV-prevalent settings should
receive at least 6 months of rifampicin treatment regimen (strong recommendation, high-quality
of evidence). The optimal dosing frequency is daily during the intensive and continuation phases.

Children living with HIV who have any of the following symptoms – poor weight gain, fever or
current cough or contact history with a TB case – may have TB and should be evaluated for TB and
other conditions. If the evaluation shows no TB, children should be offered IPT regardless of their
age.