WHO_HTM_TB_2010_13_1

Given the risk of drug-induced hepatotoxicity, WHO recommends the following
dosages of antituberculosis medicines for the treatment of tuberculosis in children:
isoniazid (H) – 10 mg/kg (range 10–15 mg/kg); maximum dose 300 mg/day
rifampicin (R) – 15 mg/kg (range 10–20 mg/kg); maximum dose 600 mg/day
pyrazinamide (Z) – 35 mg/kg (30–40 mg/kg)
ethambutol (E) – 20 mg/kg (15–25 mg/kg).