WHO_HTM_TB_2010_13_3

Children with suspected or confirmed pulmonary tuberculosis or tuberculous
peripheral lymphadenitis who live in settings with low HIV prevalence or low
resistance to isoniazid and children who are HIV-negative can be treated with a threedrug regimen (HRZ) for 2 months followed by a two-drug (HR) regimen for 4 months at the following dosages:
isoniazid (H) – 10 mg/kg (range 10–15 mg/kg); maximum dose 300 mg/day
rifampicin (R) – 15 mg/kg (range 10–20 mg/kg); maximum dose 600 mg/day
pyrazinamide (Z) – 35 mg/kg (30–40 mg/kg).