Abbreviations and acronyms

AlereLAM

Alere Determine™ TB LAM Ag

BD

Becton Dickinson

cfu

colony forming units

CI

confidence interval

CRS

composite reference standard

CSF

cerebrospinal fluid

DALY

disability-adjusted life year

DIAMA

Diagnostics for Multidrug Resistant Tuberculosis in Africa

DNA

deoxyribonucleic acid

DR-TB

drug-resistant tuberculosis

DST

drug susceptibility testing

ERG

External review Group

FIND

Foundation for Innovative New Diagnostics

FL-LPA

first-line line probe assay

FujiLAM

Fujifilm SILVAMP TB LAM

GDG

Guideline development group

GRADE

Grading of Recommendations Assessment, Development and Evaluation

HIV

human immunodeficiency virus

ICER

incremental cost–effectiveness ratio

LAM

lipoarabinomannan

LAMP

loop-mediated isothermal amplification

LF-LAM

lateral flow urine lipoarabinomannan assay

LMIC

low- and middle-income countries

LoD

limit of detection

LPA

line-probe assay

MDR

multidrug-resistant

MDR-TB

multidrug-resistant tuberculosis

MDR/RR-TB

multidrug-resistant tuberculosis or rifampicin-resistant tuberculosis

MRS

microbiological reference standard

Mtb

Mycobacterium tuberculosis

MTBC

Mycobacterium tuberculosis complex

NAAT

nucleic acid amplification test

NAT

nucleic acid test

NGS

next-generation sequencing

NTP

national TB programme

PCR

polymerase chain reaction

PICO

population, intervention, comparator and outcome

PLHIV

people living with HIV

PZA

pyrazinamide

QUADAS

quality assessment of diagnostic accuracy studies

QES

quality evidence synthesis

RIF

rifampicin

RNA

ribonucleic acid

RRDR

rifampicin resistance determining region

RR-TB

rifampicin-resistant tuberculosis

SL-LPA

second-line line probe assay

SRL

Supranational TB Reference Laboratory

STARD

Standards for Reporting Diagnostic Accuracy Studies

TB

tuberculosis

USA

United States of America

USAID

United States Agency for International Development

UV

ultraviolet

WGS

whole genome sequencing

WHO

World Health Organization

WTP

willingness-to-pay

XDR

extensively drug-resistant

XDR-TB

extensively drug-resistant tuberculosis

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