3.3.5. Options for TB preventive treatment regimens: drug-susceptible TB

The following options for TPT are recommended by WHO for use in children and adolescents:

  • 6 months or 9 months of isoniazid daily (6H or 9H) (all ages); or
  • 3 months of isoniazid plus rifapentine weekly (3HP) (age 2 years and over); or
  • 3 months of isoniazid plus rifampicin daily (3HR) (all ages).

1 month of daily isoniazid plus rifapentine (1HP) (aged 13 years and over) or 4 months of daily rifampicin (4R) (all ages) may be offered as alternative regimens.


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