5.2.6. Treatment of drug-susceptible extrapulmonary TB in children and adolescents

Children aged between 3 months and 16 years with EPTB limited to peripheral lymph nodes (i.e. without involvement of other sites of disease) should be treated with the shorter regimen (2HRZ(E)/2HR). Children with forms of drug-susceptible EPTB other than TBM and osteoarticular TB should be treated with a 6-month treatment regimen of 2HRZE/4HR. Children with osteoarticular TB should be treated with 2HRZE/10HR. Children with TBM should be treated with 2HRZE/10HR or the newly recommended alternative short intensive treatment regimen composed of 6 months of isoniazid, rifampicin, pyrazinamide and ethionamide (6HRZEto).

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