The production and writing of this document, WHO operational handbook on tuberculosis Module 4: Treatment – drug-susceptible tuberculosis treatment, was coordinated by Fuad Mirzayev, with the support of Medea Gegia and Linh Nguyen, under the guidance of Matteo Zignol and the overall direction of Tereza Kasaeva, Director of the World Health Organization (WHO) Global Tuberculosis Programme (WHO/GTB). Significant input to finalize the document was provided by Giovanni Battista Migliori, WHO Collaborating Centre for Tuberculosis and Lung Diseases; Fondazione S. Maugeri, Care and Research Institute, Tradate, Italy; and Lia D’Ambrosio, Public Health Consulting Group, Lugano, Switzerland. Colleagues from the WHO/GTB – Annemieke Brands, Dennis Falzon, Tiziana Masini, Sabine Verkuijl and Kerri Viney – also contributed to this handbook. The external review group comprised Anna Cristina Carvalho, Lisa Chen, Jeremiah Chakaya, Alberto Matteelli, Mario Raviglione and Simon Tiberi.

WHO acknowledges and appreciates the time and support of all those who have contributed to these efforts, and gratefully acknowledges the contribution of all experts involved in the production of this operational handbook. The development of this document was funded by grants provided to WHO by the United States Agency for International Development.

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