The update of this operational handbook was led by Nazir Ahmed Ismail, Carl-Michael Nathanson, and Alexei Korobitsyn, with support from Cecily Miller and Matteo Zignol, and under the overall direction of Tereza Kasaeva, Director of the World Health Organization (WHO) Global TB Programme (WHO/GTB). The WHO/GTB gratefully acknowledges Thomas Shinnick, independent consultant, Atlanta (GA), United States of America (USA) for his work in updating the document and the support of the following experts who have contributed to the review of the document: David Branigan, Treatment Action Group, USA; Patricia Hall, US Centers for Disease Control and Prevention, USA; Rumina Hasan, Department of Pathology and Microbiology, Aga Khan University, Pakistan; Brian Kaiser, Global Drug Facility, Stop TB Partnership, Switzerland; Shaheed V Omar, National Institute for Communicable Diseases and the National Health Laboratory Service, South Africa; Mark Nicol, University of Western Australia, Australia; Andrea Cabibbe, San Raffaele Supranational TB Reference Laboratory, Italy; and Wayne Van Gemert, TB Diagnostics Market Strategies, Stop TB Partnership, Switzerland.

Christopher Dobosz developed all figures.

This product was developed with support from the United States Agency for International Development (USAID).

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