Abbreviations

AFB

acid-fast bacilli

AHD

advanced HIV disease

AIDS

acquired immunodeficiency syndrome

ART

antiretroviral therapy

CC

critical concentration

CI

confidence interval

CSF

cerebrospinal fluid

DNA

deoxyribonucleic acid

DR-TB

drug-resistant tuberculosis

DST

drug-susceptibility testing

EQA

external quality assessment

FIND

Foundation for Innovative New Diagnostics

FL-LPA

line-probe assay for first-line drugs

GDG

Guideline Development Group

GLI

Global Laboratory Initiative

GTB

Global TB Programme

HIV

human immunodeficiency virus

Hr-TB

isoniazid-resistant, rifampicin-susceptible TB

IT

information technology

LAM

lipoarabinomannan

LAMP

loop-mediated isothermal amplification

LF-LAM

lateral flow lipoarabinomannan assay

LOD

limit of detection

LPA

line-probe assay

MDR/RR-TB

multidrug- or rifampicin-resistant tuberculosis

MIC

minimal inhibitory concentration

MGIT

mycobacterial growth indicator tube

MoH

ministry of health

MTBC

Mycobacterium tuberculosis complex bacteria

mWRD

molecular WHO-recommended rapid diagnostic test

NAAT

nucleic acid amplification test

NGS

next-generation sequencing

NTP

national TB programme

NTRL

national TB reference laboratory

PCR

polymerase chain reaction

PLHIV

people living with HIV/AIDS

QA

quality assurance

QC

quality control

RRDR

RIF-resistance-determining region

RR-TB

rifampicin-resistant tuberculosis

SARS-CoV-2

severe acute respiratory syndrome coronavirus 2

SL-LPA

line-probe assay for second-line drugs

SOP

standard operating procedure

SRL

supranational reference laboratory

TB

tuberculosis

T

melting temperature

TWG

technical working group

USA

United States of America

WHO

World Health Organization

WRD

WHO-recommended rapid diagnostic

XDR-TB

extensively drug-resistant tuberculosis

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