Children with peripheral lymph node TB

Although the numbers of children with peripheral lymph node TB in the SHINE trial were small (N = 19 in the 16-week arm, N = 21 in the 24-week arm), there was no difference in the proportion of unfavourable outcomes between the two arms (86). These results may provide reassurance for clinicians regarding a seemingly delayed clinical response to TB treatment, frequently seen in children with peripheral lymph node TB (where lymph nodes remain enlarged even after treatment), even if these children are treated for 4 months.

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