3.3 Tools for screening for TB disease among people living with HIV

11. Among adults and adolescents living with HIV, systematic screening for TB disease should be conducted using the WHO-recommended four symptom screen and those who report any one of the symptoms of current cough, fever, weight loss or night sweats may have TB and should be evaluated for TB and other diseases

(existing recommendation: strong recommendation, moderate certainty of evidence).

12. Among adults and adolescents living with HIV, C-reactive protein with a cut-off of > 5 mg/L may be used to screen for TB disease

(new recommendation: conditional recommendation, low certainty of evidence for test accuracy).

13. Among adults and adolescents living with HIV, chest X-ray may be used to screen for TB disease

(new recommendation: conditional recommendation, moderate certainty of evidence for test accuracy).

14. Among adults and adolescents living with HIV, molecular WHO-recommended rapid diagnostic tests may be used to screen for TB disease

(new recommendation: conditional recommendation, moderate certainty of evidence for test accuracy).

15. Adult and adolescent inpatients with HIV in medical wards where the TB prevalence is > 10% should be tested systematically for TB disease with a molecular WHO-recommended rapid diagnostic test

(new recommendation: strong recommendation, moderate certainty of evidence for test accuracy).

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