Advanced HIV disease: for adults, adolescents, and children aged 5 years or more, “advanced HIV disease” is defined as a CD4 cell count of less than 200 cells/mm³ or a WHO clinical stage 3 or 4 event at presentation for care. All children with HIV aged under 5 years should be considered as having advanced disease at presentation.
Age groups: the following definitions for adults and children are used in these guidelines for the purpose of implementing recommendations (countries may have other definitions under their national regulations)³:
- an adult is a person aged 15 years and older;
- a child is a person aged under 15 years.
Grading of Recommendations Assessment, Development and Evaluation (GRADE): a system for rating quality of evidence and strength of recommendations; the GRADE approach is explicit, comprehensive, transparent and pragmatic, and is increasingly being adopted by organizations worldwide.
Inpatient health care setting: a health care facility where patients are admitted and assigned a bed while undergoing diagnosis and receiving treatment and care, for at least one overnight stay.
Outpatient health care setting: a health care facility where patients are undergoing diagnosis and receiving treatment and care but are not admitted for an overnight stay (e.g. an ambulatory clinic or a dispensary).
³ In Section 2.2. Lateral flow urine lipoarabinomannan assay the following definitions for adults, adolescents and children were used: an adult is a person older than 19 years of age; an adolescent is a person 10–19 years of age inclusive; and a child is a person under 10 years of age.