Comorbidity: A concurrent disease or health condition in a person with TB.

Disorders due to substance use: According to the International Classification of Diseases (ICD)-11 (8), the term “disorders due to substance use” refers to a group of disorders that arise from a single or repeated use of substances that have psychoactive properties, including certain medications. For the purposes of this operational handbook, “disorders due to substance use” is divided into “disorders due to alcohol use” (or “alcohol use disorders”), which refers specifically to the use of alcohol, and “disorders due to drug use” (or “drug use disorders”), which refers to the use of psychoactive substances other than alcohol and nicotine.

Mental disorder: As defined by the International Classification of Diseases 11th Revision (ICD-11) (8), a mental disorder is a syndrome characterized by clinically significant disturbance in an individual’s cognition, emotional regulation, or behaviour that reflects a dysfunction in the psychological, biological or developmental processes that underlie mental and behavioural functioning. These disturbances are usually associated with stress or impairment in personal, family, social, educational, occupational or other important areas of functioning.

Mental health condition: A broad term covering mental disorders and psychosocial disabilities. It also covers other mental states associated with significant distress, impairment in functioning or risk of self-harm.

People-centred services: A human rights-based approach to care that consciously adopts the perspectives of individuals, carers, families and communities as participants in, and beneficiaries of, trusted health systems that respect social preferences and are organized around the comprehensive needs of people rather than individual diseases (9).

Psychosocial disability: Aligned with the Convention on the Rights of Persons with Disabilities, psychosocial disability is disability that rises when someone with a long-term mental impairment interacts with various barriers that may hinder their full and effective participation in society on an equal basis with others.

Tuberculosis (TB): The disease state due to Mycobacterium tuberculosis (10). It is commonly referred to as “TB disease” to distinguish it from TB infection.

Tuberculosis (TB) infection: state of persistent immune response to stimulation by Mycobacterium tuberculosis antigens with no evidence of clinically manifest active TB (10).

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