Optic neuritis

Early signs of ethambutol toxicity can be tested in older children using a colour perception test for red–green colour deficiencies (e.g. Ishihara test cards). Monitoring for optic neuritis can be sought early when there is clinical concern. At WHO-recommended daily doses, the risk of ethambutol toxicity is very low for treatment duration of 2 months, and ethambutol should be used in TB treatment regimens in children of all ages as per WHO recommendations (89). If optic neuritis due to ethambutol is diagnosed, ethambutol should be omitted from the regimen.

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