RetouraDSM
active tuberculosis drug safety monitoring and management
AIDS
acquired immunodeficiency syndrome
aOR
adjusted odds ratio
ART
antiretroviral therapy
ARV
antiretroviral
BMI
body mass index
BPaL
a regimen of bedaquiline, pretomanid and linezolid
BPaLC
a regimen of bedaquiline, pretomanid, linezolid and clofazimine
BPaLM
a regimen of bedaquiline, pretomanid, linezolid and moxifloxacin
CB
clinical breakpoint
CC
critical concentration
CI
confidence interval
CNS
central nervous system
DRS
drug-resistance surveillance
DR-TB
drug-resistant tuberculosis
DST
drug susceptibility testing
ECG
electrocardiography
FDC
fixed-dose combination (of medicines)
GDF
Global Drug Facility
GDG
Guideline Development Group
GRADE
Grading of Recommendations Assessment, Development and Evaluation
HBV
hepatitis B virus
HCV
hepatitis C virus
HIV
human immunodeficiency virus
HR
isoniazid–rifampicin
HRZE
isoniazid–rifampicin–ethambutol–pyrazinamide
(H)RZE
(isoniazid optional)–rifampicin–ethambutol–pyrazinamide
Hr-TB
rifampicin-susceptible, isoniazid-resistant tuberculosis
IPD
individual patient data (or dataset)
IV
intravenous
LPA
line probe assay
MDR-TB
multidrug-resistant tuberculosis
MDR/RR-TB
multidrug- or rifampicin-resistant tuberculosis
MGIT
mycobacterial growth indicator tube
MIC
minimum inhibitory concentration
NAAT
nucleic acid amplification test
NTP
national tuberculosis programme
People with HIV
people living with HIV
pre-XDR-TB
pre-extensively drug-resistant tuberculosis
RCT
randomized controlled trial
rGLC
regional Green Light Committee
RR-TB
rifampicin-resistant tuberculosis
SoC
standard of care
TB
tuberculosis
TDM
therapeutic drug monitoring
WHO
World Health Organization
WHO/GTB
World Health Organization Global Tuberculosis Programme
XDR-TB
extensively drug-resistant tuberculosis
TB medicines
Am
amikacin
B or Bdq
bedaquiline
C or Cfz
clofazimine
Cs
cycloserine
Dlm
delamanid
E
ethambutol
Eto
ethionamide
H
isoniazid
Hh
isoniazid high dose
Ipm–Cln
imipenem–cilastatin
L or Lzd
linezolid
Lfx
levofloxacin
M or Mfx
moxifloxacin
Mpm
meropenem
P or Rpt
rifapentine
Pa
pretomanid
PAS
p-aminosalicylic acid
Pto
prothionamide
R
rifampicin
S
streptomycin
Z
pyrazinamide